Can I take the Health & Her Supplements with HRT?

We regularly review the Summary of Product Characteristics (SPCs) for 27 commonly prescribed HRT medicines. The SPC is an official document approved by the Medicines and Healthcare products Regulatory Agency and used by healthcare professionals, such as doctors, nurses and pharmacists. It describes a medicinal product's properties and the conditions for its safe use. The SPC includes the latest information on known contra-indications or interactions of HRT with other medicines, nutrients and foods.

Our results show that there are no known contra-indications or interactions of the ingredients contained within this product and HRT. 

As safety information can change at any time, we always advise that you also check the medicine's patient information leaflet provided with your HRT medicine to see if any ingredients in this product are contraindicated to the medicine in question. If you're still unsure, or have any concerns, please consult your GP.

*Checked against the lastest Summary of Product Characteristics issued by the MHRA 18Jan2024

Product name	Generic name	Contraindications/interactions with ingredients contained in Health & Her Food Supplements	Contraindications of other nutritional ingredients (not contained in Health & Her Supplements)
Elleste Duet	Generic Elleste Duet 1mg tablets Generic Elleste Duet 2mg tablets	None	Cytochrome P450 inducers (e.g. St John's Wort).
Elleste Duet Conti	Estradiol 2mg / Norethisterone acetate 1mg tablets	None	Cytochrome P450 inducers (e.g. St John's Wort).
Elleste Solo	Estradiol 1mg tablets Estradiol 2mg tablets	None	Cytochrome P450 inducers (e.g. St John's Wort).
Estraderm MX	Estradiol 25micrograms/24hours transdermal patches Estradiol 50micrograms/24hours transdermal patches Estradiol 75micrograms/24hours transdermal patches Estradiol 100micrograms/24hours transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort) Inhibitors of CYP3A4 may increase oestradiol exposure.
Estradot	Estradiol 25micrograms/24hours transdermal patches Estradiol 37.5micrograms/24hours transdermal patches Estradiol 50micrograms/24hours transdermal patches Estradiol 75micrograms/24hours transdermal patches Estradiol 100micrograms/24hours transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort) Inhibitors of CYP3A4 may increase oestradiol exposure.
Evorel	Estradiol 25micrograms/24hours transdermal patches Estradiol 50micrograms/24hours transdermal patches Estradiol 75micrograms/24hours transdermal patches Estradiol 100micrograms/24hours transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort).
Evorel Conti	Estradiol 50micrograms/24hours / Norethisterone 170micrograms/24hours transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort).
Evorel Sequi	Generic Evorel Sequi transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort).
Femoston	Generic Femoston 1/10mg tablets Generic Femoston 2/10mg tablets	None	Inducers of P450 enzymes 2B6, 3A4, 3A5, 3A7 (e.g. St John's Wort)
Femoston Conti	Estradiol 500micrograms / Dydrogesterone 2.5mg tablets Estradiol 1mg / Dydrogesterone 5mg tablets	None	Cytochrome P450 inducers (e.g. St John's Wort).
Femseven	Estradiol 50micrograms/24hours transdermal patches Estradiol 75micrograms/24hours transdermal patches Estradiol 100micrograms/24hours transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort).
Femseven Conti	Estradiol 50micrograms/24hours / Levonorgestrel 7micrograms/24hours transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort).
FemSeven Sequi Phase 1	Estradiol 50micrograms/24hours transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort).
FemSeven Sequi Phase 2	Estradiol 50micrograms/24hours / Levonorgestrel 10micrograms/24hours transdermal patches	None	Cytochrome P450 inducers (e.g. St John's Wort).
Indivina	Estradiol valerate 1mg / Medroxyprogesterone 2.5mg tablets Estradiol valerate 1mg / Medroxyprogesterone 5mg tablets Estradiol valerate 2mg / Medroxyprogesterone 5mg table	None	Cytochrome P450 inducers (e.g. St John's Wort).
Kliofem	Estradiol 2mg / Norethisterone acetate 1mg tablets	None	Cytochrome P450 inducers (e.g. St John's Wort).
Kliovance	Estradiol 1mg / Norethisterone acetate 500microgram tablets	None	Cytochrome P450 inducers (e.g. St John's Wort).
Lenzetto	Estradiol 1.53mg/dose transdermal spray	None	Inducers of cytochrome P450 enzymes (e.g. St John's Wort) may increase oestrogen metabolism.
Livial	Tibolone 2.5mg tablets	None	Inducers of CYP3A4 (e.g. St John's Wort)
Mirena	Levonorgestrel 20micrograms/24hours intrauterine device	None	CYP3A4 inhibitors (e.g. grapefruit juice) can increase plasma concentrations of the progestin.
Oestrogel/dose	Estradiol 0.06% gel (750microgram per actuation)	None	Inducers of cytochrome P450 enzymes (e.g. St John's Wort) may increase oestrogen metabolism.
Premarin	Conjugated oestrogens 300microgram tablets Conjugated oestrogens 625microgram tablets Conjugated oestrogens 1.25mg tablets	None	Inhibitor of CYP3A4, may increase plasma concentrations of oestrogen and induce side effects (e.g. grapefruit juice) Inducers of CYP3A4, increased metabolism of oestrogen (e.g. St John's Wort).
Premique low dose	Conjugated oestrogens 300microgram / Medroxyprogesterone 1.5mg modified-release tablets	None	Cytochrome P450 enzyme inducers (e.g. St John's Wort)
Progynova	Estradiol valerate 1mg tablets Estradiol valerate 2mg tablets	None	St John's Wort reducing efficacy of HRT. Cytochrome P450 enzyme inducers. CYP3A4 inhibitors, including grapefruit juice, will prevent oestrogen metabolism and therefore increase plasma oestrogen concentrations.
Progynova TS	Estradiol 50micrograms/24hours transdermal patches Estradiol 100micrograms/24hours transdermal patches	None	St John's Wort reducing efficacy of HRT. Cytochrome P450 enzyme inducers. CYP3A4 inhibitors, including grapefruit juice, will prevent oestrogen metabolism and therefore increase plasma oestrogen concentrations.
Sandrena	Estradiol 500microgram gel sachets Estradiol 1mg gel sachets	None	Cytochrome P450 inducers St John's Wort, inducing metabolism of oestrogens.
Utrogestan	Progesterone micronised 100mg capsules	None	inhibitors of CYP450-3A4 may increase bioavailability of progesterone. Inducers of CYP450-3A4 may increase metabolism of progesterone (e.g. St John's Wort)